柯卓鋒

男， 中山大學(xué)， 教授/研究員/教授級(jí)高工或同等級(jí)別

學(xué)習(xí)/工作經(jīng)歷

教育經(jīng)歷：
(1) 1998-09 至 2002-06, 中山大學(xué), 化學(xué), 學(xué)士
(2) 2002-09 至 2005-06, 中山大學(xué), 高分子化學(xué)與物理, 碩士
(3) 2005-09 至 2009-06, 中山大學(xué)/University of North Texas, 物理化學(xué)/理論計(jì)算化學(xué), 聯(lián)合培養(yǎng)博士
科研與學(xué)術(shù)工作經(jīng)歷：
(1) 2009-07 至 2012-04, 日本京都大學(xué)福井謙一研究所，F(xiàn)IFC Fellow
(2) 2012-04 至 2015-12, 中山大學(xué), 化學(xué)與化學(xué)工程學(xué)院, 副教授/博導(dǎo)
(3) 2016-01 至今, 中山大學(xué), 材料科學(xué)與工程學(xué)院, 副教授/教授/博導(dǎo)

研究領(lǐng)域和興趣

反應(yīng)自動(dòng)化搜索、虛擬合成智能體、通過(guò)人工智能均相催化精準(zhǔn)設(shè)計(jì)，進(jìn)行綠色可持續(xù)合成與聚合的新研究范式探索

主要業(yè)績(jī)

研究興趣：反應(yīng)自動(dòng)化搜索、虛擬合成智能體、通過(guò)人工智能均相催化精準(zhǔn)設(shè)計(jì)，進(jìn)行綠色可持續(xù)合成與聚合的新研究范式探索。近年來(lái)發(fā)展了高效、快速、經(jīng)濟(jì)的反應(yīng)機(jī)理自動(dòng)探索新方法；利用自動(dòng)搜索工具，揭示了系列復(fù)雜反應(yīng)的全新催化機(jī)理和選擇性成因；進(jìn)行機(jī)理驅(qū)動(dòng)的人工智能催化反應(yīng)精準(zhǔn)設(shè)計(jì)，通過(guò)理論指導(dǎo)實(shí)驗(yàn)成功開(kāi)發(fā)了系列原創(chuàng)的高效綠色催化反應(yīng)體系。近五年來(lái)申請(qǐng)人作為通訊作者發(fā)表了Joule, Proc. Natl. Acad. Sci.，Nat. Commun.，J. Am. Chem. Soc.，Angew. Chem. Int. Ed.，Joule，ACS Catal.論文180余篇，授權(quán)發(fā)明專利7項(xiàng)，軟著3項(xiàng)，H-index =47。主持國(guó)家高層次青年人才、廣東省卓越青年團(tuán)隊(duì)、廣東省自然科學(xué)杰出青年基金、國(guó)家自然科學(xué)基金等項(xiàng)目。曾獲廣東特支百千萬(wàn)工程青年拔尖人才和日本福井謙一FIFC Fellow?，F(xiàn)任Communications in Computational Chemistry編委， Chinese Chemical Letters青年編委、Molecules客座編委、廣東省人工智能化學(xué)委員會(huì)副主任委員、廣州市重大行政決策論證專家等。

代表成果

1 Hai-Hua Huang, Ji-Hong Zhang, Miao Dai, Lianglin Liu, Zongren Ye, Jiahao Liu, Di-Chang Zhong, Jia-Wei Wang, Cunyuan Zhao, and Zhuofeng Ke*. Dual electronic effects achieving a high-performance Ni(II) pincer catalyst for CO2 photoreduction in a noble-metal-free system. Proc. Natl. Acad. Sci. 2022, 119, e2119267119. DOI：10.1073/pnas.2119267119.
2 Bo Yan#; Yinwu Li#; Weiwei Cao#; Zhiping Zeng, Pu Liu, Zhuofeng Ke*; and Guowei Yang*; Highly efficient and highly selective CO2 reduction to CO driven by laser, Joule, 6, 2735–2744. DOI: 10.1016/j.joule.2022.11.005.
3 Weiwei Cao, Yinwu Li, Bo Yan, Zhiping Zeng, Pu Liu, Rui Li, Jiuxing Jiang, Zhuofeng Ke*, and Guowei Yang* Catalyst-Free Activation and Fixation of Nitrogen by Laser-Induced Conversion. J. Am. Chem. Soc. 2024, 146, 14765?14775, doi: 10.1021/jacs.4c02631.
4 Xiangwen Tan, Yaru Jing, Jiahao Wu, Jiatian Li, Zhenjie Yang, Wanqing Wu, Zhuofeng Ke*, Huanfeng Jiang*. Palladium Catalyzed ortho-C(sp2)–H Activation/Cyclization of Aryl Amines Assisted by Imine and Vinylacetic Acid. Nat. Commun. 2024, 15, 9877. DOI: 10.1038/s41467-024-54018-2
5 Qian Gao, Yinwu Li, Lili Chen, Liang-Jun Xie, Xiangfeng Shao, Zhuofeng Ke*, Senmiao Xu*. Enantioselctive α?C(sp3)?H Borylation of Masked Primary Alcohols Enabled by Iridium Catalysis. J. Am. Chem. Soc. 2025, 147, 1, 88–95. DOI: 10.1021/jacs.4c14890
6 Zhe Chen, Laofeng Ouyang, Ning Wang, Weikang Li, Zhuofeng Ke*. Remote C-H Bond Cooperation Strategy Enabled Silver Catalyzed Borrowing Hydrogen Reactions. Chem. Sci. 2025, 16, 163-170. DOI: 10.1039/d4sc05486e
7 Yizhen Chen?, Peifeng Su?, Dongmin Wang, Zhuofeng Ke* & Gengwen Tan*. Molecular-strain induced phosphinidene reactivity of a phosphanorcaradiene. Nat. Commun., 2024, 15, 4579. DOI：10.1038/s41467-024-49042-1
8 Yongliang Wei, Jingxing Jiang, Yaru Jing, Zhuofeng Ke*, Liming Zhang*. Bifunctional Ligand-Enabled Gold-Catalyzed Umpolung Propargyl C-H Functionalization via Reactive Gold Allenylidene Intermediates. Angew. Chem. Int. Ed., 2024, 63, e202402286. Doi: 10.1002/anie.202402286.
9 Yu Qian*?, Jie Tang?, Jie Tang?, Xiaoyu Zhou?, Jian Luo, Xiaoyan Yang, Zhuofeng Ke*, and Wenhao Hu* Enantioselective Multi-Functionalization with Rh Carbynoids. J. Am. Chem. Soc. 2023, 145, 48, 26403–26411. DOI: 10.1021/jacs.3c10460
10 Can Yang?, Xiaoyu Zhou?, Lixing Shen, Zhuofeng Ke*, Huanfeng Jiang, Wei Zeng*. Mn(I)-catalyzed sigmatropic rearrangement of β, γ-unsaturated alcohols. Nat. Commun., 2023, 14, 1862. DOI: 10.1038/s41467-023-37299-x

*以上信息由高級(jí)會(huì)員個(gè)人更新和維護(hù)。