樂學(xué)義

男， 華南農(nóng)業(yè)大學(xué)， 教授/研究員/教授級(jí)高工或同等級(jí)別

學(xué)習(xí)/工作經(jīng)歷

1978.09-1982.07, 湖北師范大學(xué)(原黃石師范學(xué)院）化學(xué)系,本科生
1982.08-1985.08, 湖北省應(yīng)城市教師進(jìn)修學(xué)校,教師
1985.09-1988.06, 華中師范大學(xué)化學(xué)系,碩士研究生
1988.06-1993.08, 湖北工程學(xué)院（原孝感師范?？茖W(xué)校）化學(xué)系,講師
1993.09-1996.06, 中山大學(xué)化學(xué)化工學(xué)院,博士研究生
1997.12-2001.12, 華南農(nóng)業(yè)大學(xué)理學(xué)院，副教授、碩士生導(dǎo)師(1999.06-)，期間擔(dān)任應(yīng)用化學(xué)系副主任(2001.03-2001.04) 、理學(xué)院副院長(zhǎng)兼任應(yīng)用化學(xué)系主任（2001.05- 2006.12）
2001.12-2014.12，華南農(nóng)業(yè)大學(xué)理學(xué)院,教授(破格) 、博士生導(dǎo)師(2005/06-)，期間擔(dān)任理學(xué)院院長(zhǎng)（2007/01-2014/12）
2015.01-現(xiàn)在, 華南農(nóng)業(yè)大學(xué)材料與能源學(xué)院應(yīng)用化學(xué)系,教授,博(碩)士生導(dǎo)師

研究領(lǐng)域和興趣

生物無(wú)機(jī)化學(xué)

主要業(yè)績(jī)

長(zhǎng)期從事生物無(wú)機(jī)化學(xué)、藥物化學(xué)、食品科學(xué)等交叉學(xué)科研究,先后承擔(dān)省部級(jí)以上科研項(xiàng)目20余項(xiàng),已公開發(fā)表學(xué)術(shù)論文180多篇,其中90余篇被SCI收錄,獲得國(guó)家發(fā)明專利2項(xiàng),作為主要參加人獲廣東省自然科學(xué)一等獎(jiǎng)1項(xiàng),合作出版編著1本。

代表成果

1. Dai-Hong Cai, Chun-Lian Zhang, Qi-Yan Liu, Liang He, Yun-Jun Liu, Ya-Hong Xiong, Xue-Yi Le*. Synthesis, DNA binding, antibacterial and anticancer properties of two novel water-soluble copper(II)
complexes containing gluconate. European Journal of Medicinal Chemistry,213( 2021), doi.org/ 10.1016/ j.ejmech. 2021.113182
2. Yong-Yu Qi, Qian Gan , Ya-Xian Liu, Ya-Hong Xiong, Zong-Wan Mao, Xue-Yi Le*. Two new Cu(II) dipeptide complexes based on 5-methyl-2-(2’-pyridyl)benzimidazole as potential antimicrobial and anticancer drugs:Special exploration of their possible anticancer mechanism. European Journal of Medicinal Chemistry, 154(2018), DOI: 10.1016/j.ejmech.2018.05.023;
3．Chun-Lian Zhang, Ya-Xian Liu, Xue-Mei Zhang, Shi Chen, Fang Shen, Ya-Hong Xiong, Wei Liu,, Zong-Wan Mao, Xue-Yi Le*. Synthesis, characterization, DNA/HSA interactions and in vitro cytotoxic activities of two novel water-soluble copper(II) complexes with 1,3,5-triazine derivative ligand and amino acids. Materials Science & Engineering C, 91(2018), DOI: 10.1016/j.msec.2018.05.065;
4.Yujia Liu, Yanxue Cai, Danyang Ying, Yinlian Fu, Yahong Xiong, Xueyi Le*. Ovalbumin as a carrier to significantly enhance the aqueous solubility and photostability of curcumin: Interaction and binding mechanism study. International Journal of Biological Macromolecules, 116(2018), DOI: 10.1016/j.ijbiomac.2018.05.089;
5. Xia-Bing Fu, Dan-Dan Liu, Yuan Lin, Wei Hu, Zong-Wan Mao and Xue-Yi Le*. Water-soluble DNA minor groove binders as potential chemotherapeutic agents: synthesis, characterization, DNA binding and cleavage, antioxidation, cytotoxicity and HSA interactions. Dalton Transaction, 43(2014), DOI: 10.1039/c3dt53577k;

*以上信息由高級(jí)會(huì)員個(gè)人更新和維護(hù)。