何彥

男， 清華大學(xué)化學(xué)系， 教授/研究員/教授級(jí)高工或同等級(jí)別

學(xué)習(xí)/工作經(jīng)歷

1990.09—1995.07，北京大學(xué)，化學(xué)系，學(xué)士
1995.08—2001.12，The University of Iowa，化學(xué)系，博士
1998.01—2001.05，The University of Iowa，計(jì)算機(jī)系，碩士
2002.09—2005.05，Iowa State University-Ames Lab，博士后
2005.06—2016.07，湖南大學(xué)，化學(xué)化工學(xué)院，教授、博士生導(dǎo)師
2015.09—至今，清華大學(xué)，化學(xué)系，教授、博士生導(dǎo)師

研究領(lǐng)域和興趣

分析化學(xué)；單分子單細(xì)胞光譜、光學(xué)顯微成像技術(shù)，復(fù)雜體系時(shí)空動(dòng)態(tài)分析

主要業(yè)績

長期從事單分子單細(xì)胞成像分析研究?；趩蝹€(gè)金屬納米顆粒共振光散射特性，發(fā)展了一系列非熒光單分子成像技術(shù)，以納米顆粒動(dòng)態(tài)自組裝、納米顆粒在活體細(xì)胞和細(xì)胞集群中的動(dòng)態(tài)行為等為研究體系，系統(tǒng)地考察了單個(gè)納米顆粒與復(fù)雜體系間的動(dòng)態(tài)相互作用。2007年入選國家“新世紀(jì)優(yōu)秀人才支持計(jì)劃”，2012年獲湖南省自然科學(xué)杰出青年基金，2014年獲國家杰出青年科學(xué)基金。近年來在包括JACS、Angew Chem、Nat Commun、Anal Chem、Acs Nano等期刊上發(fā)表論文30余篇。

代表成果

1、J.-J. Feng, Z.-X. Zhang, X.-D. Wen, J.-F. Xue, Y. He*, Single Nanoparticle Tracking Reveals Efficient Long-Distance Undercurrent Transport in Upper Fluid of Bacterial Swarms, iScience. 2019, 22, 123-132. DOI: 10.1016/j.isci.2019.11.012
2、H. Sun, Z.-H. Wang*, Y. He*, Direct Observation of Spatiotemporal Heterogeneous Gelation by Rotational Tracking of a Single Anisotropic Nanoprobe, ACS Nano. 2019, 13 (10), 11334-11342. DOI: 10.1021/acsnano.9b04491
3、Q. Pan, H.-S. Zhao, X.-J. Lin, Y. He*, Spatiotemporal Heterogeneity of Reactions in Solution Observed with High-Speed Single-Nanorod Rotational Sensing, Angew. Chem. Int. Ed. 2019, 58 (25), 8389-8393. DOI: 10.1002/anie.201901550
4、X. Cao, J.-J. Feng, Q. Pan, B. Xiong, Y. He*, E. S. Yeung, Direct Imaging of Single Plasmonic Metal Nanoparticles in Capillary with Laser Light-Sheet Scattering Imaging, Anal. Chem. 2017, 89 (5), 2692-2697. DOI: 10.1021/acs.analchem.6b03844
5、B. Xiong*, Z.-R. Huang, H.-Y. Zou, C.-Y. Qiao, Y. He*, E. S. Yeung, Single Plasmonic Nanosprings for Visualizing Reactive-Oxygen-Species-Activated Localized Mechanical Force Transduction in Live Cells, ACS Nano. 2017, 11 (1), 541-548. DOI: 10.1021/acsnano.6b06591
6、Peng, Y.; Xiong, B.; Peng, L.; Li, H.; He, Y.*; Yeung, E. S.*, Recent Advances in Optical Imaging with Anisotropic Plasmonic Nanoparticles. Analytical Chemical. 2015, 87 (1), 200-215. DOI: 10.1021/ac504061p
7、Xu, D.; He, Y.*; Yeung, E. S., Direct Observation of the Orientation Dynamics of Single Protein-Coated Nanoparticles at Liquid/Solid Interfaces. Angewandte Chemie International Edition. 2014, 53 (27), 6951-6955. DOI: 10.1002/anie.201400025
8、Xiong, B.; Zhou, R.; Hao, J.; Jia, Y.; He, Y.*; Yeung, E. S., Highly sensitive sulphide mapping in live cells by kinetic spectral analysis of single Au-Ag core-shell nanoparticles. Nature Communications. 2013, 4:1708. DOI: 10.1038/ncomms2722
9、Zhou, R.; Zhou, H.; Xiong, B.; He, Y.*; Yeung, E. S., Pericellular Matrix Enhances Retention and Cellular Uptake of Nanoparticles. Journal of the American Chemical Society. 2012, 134 (32), 13404-13409. DOI: 10.1021/ja304119w
10、 Xiao, L.; Qiao, Y.; He, Y.*; Yeung, E. S., Imaging Translational and Rotational Diffusion of Single Anisotropic Nanoparticles with Planar Illumination Microscopy. Journal of the American Chemical Society. 2011, 133 (27), 10638-10645. DOI: 10.1021/ja203289m

*以上信息由高級(jí)會(huì)員個(gè)人更新和維護(hù)。