祝詩發(fā)

男， 華南理工大學， 教授/研究員/教授級高工或同等級別

學習/工作經歷

1997.09-2001.07 湖南大學，本科學生
2001.09-2006.07 中科院上海有機所，博士生
2006.09-2007.01 Syracuse University，博士后
2007.01-2009.01 University of South Florida ，博士后
2009.05-2013.08 華南理工大學，副教授
2013.09-現(xiàn)在 華南理工大學，教授
2024.01-現(xiàn)在 華南理工大學，二級教授，興華杰出學者

研究領域和興趣

有機化學

主要業(yè)績

主要從事碳-碳三鍵化學，已在Chem. Soc. Rev., J. Am. Chem. Soc., Angew. Chem. Int. Ed., Chem等雜志發(fā)表SCI論文80余篇，授權PCT專利、美國專利、中國發(fā)明專利共二十余件。承擔了包括教育部新世紀優(yōu)秀人才計劃、國家自然科學基金、973項目子課題、國家重點研發(fā)計劃子課題、廣東省自然科學基金等項目二十余項。
2009年5月進入華南理工大學化學與化工學院工作，2010年入選“教育部新世紀優(yōu)秀人才支持計劃”，2014年獲“國家自然科學基金優(yōu)秀青年基金”資助，同年入選“廣東省千百十工程省級培養(yǎng)對象”，2015年入選“廣東省特支計劃百千萬工程領軍人才”，2016年入選“科技部中青年科技創(chuàng)新領軍人才”，2017年入選國家“萬人計劃”領軍人才。目前是廣東省化學會理事，廣州市化學化工學會理事，廣東省化學會“有機化學專業(yè)委員會副主任”。

代表成果

[1] Wendeng Li, Rui Wu, Hao Ruan, Bo Xiao, Xiang Gao, Huanfeng Jiang, Kai Chen, Tian-Yu Sun*, and Shifa Zhu*, Axial Ligand Enables Synthesis of Allenylsilane through Dirhodium(II) Catalysis, Angew. Chem. Int. Ed. 2024, 63, e202409332.
[2] Chuntao Wang, Rui Wu, Kai Chen*, Shifa Zhu*, Enantioselective Synthesis of Biscyclopropanes Using Alkynes as Dicarbene Equivalents, Angew. Chem. Int. Ed. 2023, 62, e202305864.
[3] Shiwei Lü, Zipeng Wang, Xiang Gao, Kai Chen*, Shifa Zhu*, 1,2-Difunctionalization of Acetylene Enabled by Light, Angew. Chem. Int. Ed. 2023, 62, e202300268.
[4] Boxiang Liu, Zhicong Lin, Yu Wang, Tairan Cheng, Tongxiang Cao, Shifa Zhu*, Trimerization of Acetylene and Alkene: Rapid Access to Polyenes, CCS Chem., 2023, 5, 1077-1085.
[5] Shiwei Lü, Zipeng Wang and Shifa Zhu*, Thiol-Yne Click Chemistry of Acetylene-Enabled Macrocyclization, Nat. Commun.2022, 13, 5001.
[6] Bo Yang, Shaodong Lu, Yongdong Wang and Shifa Zhu*, Diverse Synthesis of C2-Linked Functionalized Molecules via Molecular Glue Strategy with Acetylene, Nat. Commun. 2022, 13, 1858.
[7] Rui Wu, Jiajun Lu, Tongxiang Cao, Jun Ma, Kai Chen*, Shifa Zhu*, Enantioselective Rh(II)-Catalyzed Desymmetric Cycloisomerization of Diynes: Constructing Furan-Fused Dihydropiperidines with an Alkyne-Substituted Aza-Quaternary Stereocenter, J. Am. Chem. Soc., 2021, 143, 14916-14925.
[8] Yang Chen, Pingchuan Shen, Tongxiang Cao, Hao Chen, Zujin Zhao* and Shifa Zhu*, Bottom-up Modular Synthesis of Well-Defined Oligo(arylfuran)s, Nat. Commun., 2021, 12, 6165.
[9] Bo Yang, Shi-Jun Li, Yongdong Wang*, Yu Lan*, Shifa Zhu*， Hydrogen radical-shuttle (HRS)-enabled photoredox synthesis of indanones via decarboxylative annulation. Nat. Commun., 2021, 5257.
[10] Dong Zhu, Lianfen Chen, Hanlin Fan, Qinglin Yao and Shifa Zhu*, Recent Progress on Donor and Donor-Donor Carbenes, Chem. Soc. Rev. 2020, 49, 908-950.
[11] Ling Zhang, Tongxiang Cao, Huanfeng, Jiang, and Shifa Zhu*, Deconstructive Reorganization: De Novo Synthesis of Hydroxylated Benzofuran Angew. Chem. Int. Ed. 2020, 59, 4670-4677.
[12] Lianfen Chen, Kai Chen, Shifa Zhu*, Transition Metal-Catalyzed Intramolecular Nucleophilic Addition of Carbonyl Group to Alkyne, Chem 2018, 4, 1208-1262.
[13] Dong Zhu, Lianfen Chen, He Zhang, Zhiqiang Ma, Huanfeng Jiang, and Shifa Zhu*, Catalyst-Controlled Highly Chemo- and Stereoselective Allylic C-H Insertion and Cyclopropanation of Donor/Donor-Carbenes, Angew. Chem. Int. Ed. 2018, 57, 12405-12409.
[14] Tongxiang Cao, Yi Kong, Kui Luo, Lianfen Chen, and Shifa Zhu*, Cascade Claisen Rearrangement: Rapid Synthesis of Polysubstituted Salicylaldehydes and Total Synthesis of Hemigossypol and Gossypol, Angew. Chem. Int. Ed. 2018, 57, 8702-8707.
[15] Dong Zhu, Jun Ma, Kui Luo, Hongguang Fu, Li Zhang*, Shifa Zhu*, Enantioselective Intramolecular C-H insertion of Donor- and Donor/Donor-Carbenes via a Non-Diazo Approach, Angew. Chem. Int. Ed., 2016, 55, 8452-8456.
[16] Renxiao Liang, Kai Chen, Qiaohui Zhang, Jiantao Zhang, Huanfeng Jiang, Shifa Zhu*, Rapid Access to 2-Methy lene Tetrahydrofurans and γ-Lactones: A Four-Step Tandem Process, Angew. Chem. Int. Ed., 2016, 55, 2587-2591.
[17] Shifa Zhu*, Qiaohui Zhang, Kai Chen, Huanfeng Jiang, Synergistic Catalysis: Metal/Proton-Catalyzed Cyclization of Alkynones Toward Bicyclo[3.n.1]alkanones, Angew. Chem. Int. Ed., 2015, 54, 9414-9418.
[18] Shifa Zhu*, Renxiao Liang, Huanfeng Jiang, Wanqing Wu, An Efficient Route to Polysubstituted Tetrahydronaphthols: Silver-Catalyzed [4+2] Cyclization of 2-Alkylbenzaldehydes and Alkenes, Angew. Chem. Int. Ed., 2012, 51, 10861-10865.
[19] Shifa Zhu, Tongxiang Cao, Yongdong Wang; Zhihuang Huang; Polysubstituted Benzene, Preparation Method Thereof, and Method of Using the Same, 2022, 美國專利號：16/986303；
[20] 祝詩發(fā)，曹同祥，王永東，黃志鵬，具有生物活性的多取代苯化合物及其制備方法和應用，2019, PCT專利號：WO2019153954A1；
[21] 江煥峰，祝詩發(fā) 譯，[美]R.H.克拉布特里 著，過渡金屬有機化學（原著第五版），科學出版社，2012年，北京；

*以上信息由高級會員個人更新和維護。