張文科

男， 吉林大學(xué)超分子結(jié)構(gòu)與材料國家重點實驗室， 教授/研究員/教授級高工或同等級別

學(xué)習(xí)/工作經(jīng)歷

1993.09-1997.07，吉林大學(xué)化學(xué)系，本科生
1997.09-2002.07，吉林大學(xué)化學(xué)學(xué)院，研究生（碩博連讀）
2001.04-2002.03，德國慕尼黑大學(xué)應(yīng)用物理系，博士生聯(lián)合培養(yǎng)
2003.03-2004.09，英國諾丁漢大學(xué)藥學(xué)院，博士后
2004.10-2007.05，英國諾丁漢大學(xué)化學(xué)學(xué)院，博士后
2007.06-至今，吉林大學(xué)超分子結(jié)構(gòu)與材料國家重點實驗室，教授

研究領(lǐng)域和興趣

聚合物單分子力譜與超分子相互作用，高分子結(jié)晶與熔融，生物大分子相互作用，高分子力化學(xué)

主要業(yè)績

長期從事聚合物單分子力譜研究，近年來在高分子凝聚態(tài)體系的分子間相互作用及超分子組裝推動力研究方面取得一系列重要的創(chuàng)新性成果，部分成果發(fā)表在Nat. Commun.，J. Am. Chem. Soc. 等重要國際期刊上，并受到國際同行的廣泛關(guān)注與積極評價。應(yīng)邀在國際國內(nèi)重要學(xué)術(shù)會議做邀請報告30余次（其中包括3次大會報告）。2015年獲得國家杰出青年科學(xué)基金獲資助，2017年入選科技部“創(chuàng)新人才推進計劃”中青年科技創(chuàng)新領(lǐng)軍人才，2018年入選中組部“萬人計劃”領(lǐng)軍人才。主持國家重大科研儀器研制項目（自由申請）及基金委面上等項目。擔(dān)任中國化學(xué)會高分子學(xué)科委員會、生物物理化學(xué)專業(yè)委員會、超分子化學(xué)專業(yè)委員會委員，AIMS Biophysics及Langmuir期刊編委。

代表成果

[1] Y. Song, Z. Ma, W. K. Zhang*, Manipulation of a single polymer chain: from the nanomechanical properties to dynamic structure evolution, Macromolecules, 2022, 55, 4177?4199. DOI: 10.1021/acs.macromol.2c00076; (Invited Perspective, ACS Editors’ Choice)
[2] X. N. Zhang, X. Kou, W. Zhang, W. K. Zhang*, Identification of the new type of G-Quadruplex with multiple vacant sites in human telomeric DNA, CCS Chem., 2022, 4, 3023–3035.
[3] R. Yao, X. Li, N. Xiao, W. Weng*, W. K. Zhang*, Single-molecule observation of mechanical isomerization of spirothiopyran and subsequent Click addition, Nano Res., 2021, 14(8): 2654–2658. DOI:10.1007/s12274-020-3268-9;
[4] X. N. Zhang, Y. Q. Zhang and W. K. Zhang*, Dynamic topology of double-stranded telomeric DNA studied by single-molecule manipulation in vitro, Nucleic Acids Res., 2020, 48, 6458–6470. DOI: 10.1093/nar/gkaa479;
[5] Z. W. Ma, P. Yang, X. Y. Zhang, K. Jiang, Y. Song*, W. K. Zhang*, Quantifying the chain folding in polymer single crystals by single-molecule force spectroscopy, ACS Macro Lett., 2019, 8, 1194?1199. DOI: 10.1021/acsmacrolett.9b00607; (ACS Editors’ Choice)
[6] P. Yang, Y. Song, W. Feng, W. K. Zhang*, Unfolding of a single polymer chain from the single crystal by air-phase single-molecule force spectroscopy: toward better force precision and more accurate description of molecular behaviors, Macromolecules, 2018, 51, 7052?7060. DOI: 10.1021/acs.macromol.8b01544;
[7] H. Zhang, X. Li, Y. J. Lin, F. Gao, Z. Tang, P. F. Su, W. K. Zhang*, Y. Z. Xu, W. G. Weng*, R. Boulatov*, Multi-modal mechanophores based on cinnamate dimers, Nat. Commun., 2017, 8, 1147. DOI: 10.1038/s41467-017-01412-8;
[8] Y. R. Xue, X. Li, H. B. Li, W. K. Zhang*, Quantifying thiol-gold interactions towards the efficient strength control, Nat. Commun., 2014, 5:4348. DOI: 10.1038/ncomms5348; (Highly Cited Paper)
[9] N. N. Liu, B. Peng, Y. Lin, Z. H. Su, Z. W. Niu, Q. Wang, W. K. Zhang*, H. B. Li, J. C. Shen, Pulling genetic RNA out of tobacco mosaic virus using single-molecule force spectroscopy, J. Am. Chem. Soc., 2010, 132, 11036-11038. DOI:10.1021/ja1052544;
[10] K. Liu, Y. Song, W. Feng, N. N. Liu, W. K. Zhang*, X. Zhang, Extracting a single polyethylene oxide chain from a single crystal by a combination of atomic force microscopy imaging and single-molecule force spectroscopy: toward the investigation of molecular interactions in their condensed states, J. Am. Chem. Soc., 2011, 133, 3226-3229. DOI: 10.1021/ja108022h. (Highlighted by Nature Materials)

*以上信息由高級會員個人更新和維護。