楊朝勇

男， 廈門(mén)大學(xué)化學(xué)化工學(xué)院， 教授/研究員/教授級(jí)高工或同等級(jí)別

學(xué)習(xí)/工作經(jīng)歷

2008.01-至今，廈門(mén)大學(xué)化學(xué)生物學(xué)系，教授、博導(dǎo)
2006.09-2007.12，加州大學(xué)伯克利分?；瘜W(xué)系, 博士后, 導(dǎo)師: Richard Mathies
2001.08-2006.08，美國(guó)佛羅里達(dá)大學(xué)，生物分析化學(xué)博士，導(dǎo)師: 譚蔚泓
1994.09-2001.07，廈門(mén)大學(xué)化學(xué)系，本科，碩士，導(dǎo)師：王小如

研究領(lǐng)域和興趣

體外診斷新技術(shù); 細(xì)胞識(shí)別、富集與成像; 高通量單細(xì)胞測(cè)序; 生物分析化學(xué)；微流控技術(shù)在生物醫(yī)學(xué)中的應(yīng)用

主要業(yè)績(jī)

楊朝勇教授，國(guó)家杰出青年科學(xué)基金獲得者，英國(guó)皇家化學(xué)會(huì)Fellow、譜學(xué)分析與儀器教育部重點(diǎn)實(shí)驗(yàn)室副主任、中國(guó)化學(xué)會(huì)化學(xué)生物學(xué)專(zhuān)業(yè)委員會(huì)副主任。相繼于1998和2001年在廈門(mén)大學(xué)化學(xué)系獲得學(xué)士與碩士學(xué)位，2006年獲得美國(guó)佛羅里達(dá)大學(xué)博士學(xué)位，2006年9月至2007年12月在美國(guó)加州大學(xué)伯克利分校從事博士后研究。目前在Acc. Chem. Res.、PNAS、JACS、Angew. Chem. Int. Ed等學(xué)術(shù)刊物上發(fā)表論文180余篇。獲授權(quán)專(zhuān)利30余項(xiàng)。研究工作被美國(guó)Washington Times、The Scientist、英國(guó)RSC Chemistry World、歐洲Wiley Chemistry Views、JACS Spotlights、光明日?qǐng)?bào)、解放日?qǐng)?bào)等媒體與刊物做了專(zhuān)題報(bào)道。先后獲得了美國(guó)化學(xué)會(huì)分析化學(xué)研究生獎(jiǎng)、中國(guó)政府國(guó)家優(yōu)秀自費(fèi)留學(xué)生獎(jiǎng)、中美化學(xué)與化學(xué)生物學(xué)教授協(xié)會(huì)杰出教授獎(jiǎng)、中國(guó)青年分析化學(xué)家獎(jiǎng)、中國(guó)化學(xué)會(huì)-英國(guó)皇家化學(xué)會(huì)青年化學(xué)獎(jiǎng)、科技部中青年科技創(chuàng)新領(lǐng)軍人才等獎(jiǎng)項(xiàng)與榮譽(yù)。現(xiàn)任ACS Applied Bio Materials 副主編、BMC Biochemistry 副主編、Analytical Chemistry、Lab on a Chip、Talanta、Analyst、Biomicrofluidics、Journal of Analysis and Testing、Scientific Reports等期刊編委。作為項(xiàng)目負(fù)責(zé)人主持國(guó)家自然科學(xué)基金6項(xiàng)，科技部課題3項(xiàng)，包括國(guó)家重大科研儀器研制項(xiàng)目（2019），國(guó)家自然科學(xué)基金委重點(diǎn)項(xiàng)目（2018），國(guó)家杰出青年科學(xué)基金（2013）、科技部973課題、國(guó)家重點(diǎn)研發(fā)計(jì)劃合成生物學(xué)重點(diǎn)專(zhuān)項(xiàng)課題等。

代表成果

1. Cao,? J; Zheng,? Z; Sun, D; Chen, X; Cheng, R; Lv, T; An, Y; Zheng, J*; Song, J*; Wu, L*; Yang, C*; Decoder-seq enhances mRNA capture efficiency in spatial RNA sequencing. Nat. Biotechnol. 2024, DOI: https://doi.org/10.1038/s41587-023-02086-y
2. Yu, X; Ruan, W; Lin, F; Qian, W; Zou, Y; Liu, Y; Su, R; Niu, Q; Ruan, Q; Lin, W; Zhi Zhu, Zhang, H* ; Yang, C*, Digital microfluidics-based digital counting of single-cell copy number variation (dd-scCNV Seq), Proc. Natl. Acad. Sci. U. S. A., 2023, 120, e2221934120
3. Lin, S; Yin, K;Zhang, Y; Lin, F; Chen, X; Zeng, X; Guo, X; Zhang, H; Song, J*, Yang, C*. Well-TEMP-seq as a microwell-based strategy for massively parallel profiling of temporal dynamics in single-cells. Nat. Commun., 2023, 14, 1272
4. Niu, Q; Gao, J; Zhao, K; Chen, X; Lin, X; Huang, C; An, Y; Xiao, X; Wu, Q; Cui, L*; Zhang, P*; Wu, L*; Yang, C*; Fluid Nanoporous Microinterface Enables Multiscale-Enhanced Affinity Interaction for Tumor-Derived Extracellular Vesicle Detection. Proc. Natl. Acad. Sci. U. S. A., 2022, 119, e2213236119
5. Sun, M; Liu, S; Wei, X; Wan, S; Huang, M; Song, T; Lu, Y; Weng, X; Zhu, L; Chen, H*; Song, Y*; Yang, C*; Aptamer Blocking Strategy Inhibits SARS-CoV-2 Virus Infection, Angew. Chem. Int. Ed., 2021, 60, 2-9
6. Lin, B; Tian, T; Lu, Y; Liu, D; Huang, M; Zhu, L; Zhu, Z; Song, Y*; Yang, C*; Tracing Tumor-derived Exosomal PD-L1 by Dual-aptamer Activated Proximity-induced Droplet Digital PCR, Angew. Chem. Int. Ed., 2021, 7582-7586
7. Wu, L; Wang, Y; Xu,X; Liu, Y; Lin, B; Zhang, M, Zhang, J; Wan, S; Yang, C*; Tan, W*; Aptamer-Based Detection of Circulating Targets for Precision Medicine, Chem. Rev., 2021, 121, 12035–12105
8. Huang, M#; Li, T#; Xu, Y; Wei, X; Song, J; Lin,B; Zhu, Z; Song, Y*; Yang, C*; Activation of Aptamers with Gain-of-Function by Small-Molecule Clipping of Intramolecular Motifs, Angew. Chem. Int. Ed., 2021, 60, 6021-6028
9. Ruan, Q; Ruan, W; Lin, X; Wang, Y; Zou, F; Zhou, L; Zhu, Z; Yang, C*; Digital-WGS: Automated, Highly Efficient Whole-genome Sequencing of Single Cells by Digital Microfluidics, Sci. Adv., 2020, 6: eabd6454
10. Lin, L; Wu, Q; Song, J; Du, Y; Gao, J; Song, Y; Wang, W*; Yang, C*; Revealing the in vivo Growth and Division Patterns of Mouse Gut Bacteria, Sci Adv., 2020, 6, eabb2531
11. Wang, W*; Zhang, N; Du, Y; Gao, J; Li, M; Lin, L; Czajkowsky, D; Li, X*; Yang, C*; Shao, Z. Three-dimensional Quantitative Imaging of Native Microbiota Distribution in the Gut. Angew Chem. Int. Ed., 2020, 132, 2-9
12. Zhang, J; Lin, B; Wu, L; Huang, M; Li, X; Zhang, H; Song, J; Wang, W; Zhao, G*; Song, Y*; Yang, C*; DNA Nanolithography Enables Highly Ordered Recognition Interface in Microfluidic Chip for Efficient Capture and Release of Circulating Tumor Cells, Angew. Chem. Int. Ed., 2020, 59, 14115-14119
13. Lin, L; Song, J; Du, Y; Wu, Q; Gao, J; Song, Y; Yang, C*; Wang, W.*; Quantification of Bacterial Metabolic Activities in the Gut by D-Amino Acid-based in vivo Labeling, Angew. Chem. Int. Ed., 2020, 59, 11923-11926
14. Zhang, M; Zou, Y; Xu, X; Zhang, X; Gao, M; Song, J; Huang, P; Chen, Q; Zhu, Z; Lin, W; Zare, R; Yang, C *; Highly Parallel and Efficient Single Cell mRNA Sequencing with Paired Picoliter Chambers, Nat. Commun., 2020, 11, 2118
15. Wu, L; Ding, H; Qu, X; Shi, X; Yang, J; Huang, M; Zhang, J; Zhang, H; Song, J; Zhu, L; Song, Y*; Ma, Y*; Yang, C*; Fluidic Multivalent Membrane Nanointerface Enables Synergetic Enrichment of Circulating Tumor Cells with High Efficiency and Viability, J. Am. Chem. Soc., 2020, 142, 4800-4806
16. Huang, M; Yang, J; Wang, T; Song, J; Xia, J; Wu, L; Wang, W; Wu, Q; Zhu, Z; Song, Y*; Yang, C*; Homogeneous, Low-volume, Efficient and Sensitive Quantitation of Circulating Exosomal PD-L1 for Cancer Diagnosis and Immunotherapy Response Prediction, Angew. Chem. Int. Ed., 2020, 59, 4800-4805
17. Wang, W; Yang, Q; Du, Y; Zhou, X; Du, X; Wu, Q; Lin, L; Song, Y; Li, F; Yang, C*; Tan, W*; Metabolic Labeling of Peptidoglycan with NIR-II Dye Enables in vivo Imaging of Gut Microbiota, Angew. Chem. Int. Ed., 2020, 59, 2628-2633
18. Wang, W; Lin, L; Du, Y; Song, Y; Peng, X; Chen, X*; Yang, C*; Assessing the Viability of Transplanted Gut Microbiota by Sequential Tagging with D-Amino acid-based Metabolic Probes, Nature Commun., 2019, 10, 1317
19. Song, Y; Shi, Y; Huang, M; Wang, W; Wang, Y; Cheng, J; Lei, Z; Zhu, Z; Yang, C*; Bioinspired Engineering of Multivalent Aptamer-Functionalized Nanointerface to Enhance Capture and Release of Circulating Tumor Cells, Angew. Chem. Int. Ed., 2019, 58, 2236-2240
20. Chen, Y; Ke, G*; Ma, Y; Zhu, Z; Liu, M; Liu, Y; Yan, H*; Yang, C*; A Synthetic Light-Driven Substrate Channeling System for Precise Regulation of Enzyme Cascade Activity Based on DNA Origami, J. Am. Chem. Soc., 2018, 28, 8990-8996

*以上信息由高級(jí)會(huì)員個(gè)人更新和維護(hù)。